Dr Neda Nabavi

Biostimulators in facial treatment

Anti-ageing through natural regeneration

Radiesse® and polynucleotides

Effective methods to combat skin ageing

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Biostimulants are a modern and effective method of aesthetic medicine to combat skin ageing, which aims to stimulate the body's own regeneration mechanisms. They are an alternative to classic filler treatments, as they not only fill wrinkles, but also regenerate and rejuvenate the skin structure from within. In contrast to hyaluronic acid fillers, which primarily add volume, biostimulants promote the production of collagen, elastin and other important structures in the skin, which leads to an improvement in skin quality in the long term.

What are biostimulators?

Biostimulants are substances that are injected into the skin or underlying tissue to stimulate the body's own production of collagen and elastin. These two proteins are crucial for the firmness, elasticity and tautness of the skin. As we age, the natural production of these proteins decreases, leading to wrinkles, loss of volume and sagging skin.

 

The most frequently used biostimulants include

  • Radiesse® is a biostimulator based on calcium hydroxyapatite and is used for skin rejuvenation. It stimulates the body's own collagen production and thus supports the build-up of volume and the improvement of the skin structure. After injection, Radiesse® not only has an immediate plumping effect, but also stimulates the long-term production of new collagen, resulting in firmer, more elastic skin. The skin is naturally regenerated and regains its youthful firmness, with long-lasting results.
  • Radiesse® dilute is a diluted version of the classic Radiesse® and is used as a biostimulator for skin rejuvenation. It stimulates collagen production without adding significant volume and is particularly suitable for large-area applications such as the face, neck, décolleté and hands. Once injected, Radiesse® dilute promotes the formation of new collagen and elastin, resulting in improved skin firmness, hydration and texture. The result is smoother, firmer skin with a fresh, youthful appearance.
  • Polynucleotides are long chains of nucleic acids (DNA and RNA) that are used in aesthetic medicine to regenerate the skin. They work by stimulating cell repair, promoting the production of collagen and elastin and improving skin hydration. Thanks to their anti-inflammatory and regenerative properties, they strengthen the skin structure and help to reduce wrinkles and improve skin elasticity. Polynucleotides thus promote the natural regeneration of the skin and contribute to firmer, smoother and rejuvenated skin.

These biostimulants stimulate the body to naturally form new skin structures, gradually making the skin thicker, firmer and more elastic.

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How do biostimulators work?

The mechanism of the biostimulants is based on the stimulation of fibroblasts, which are responsible for the production of collagen and elastin in the skin. These proteins form the framework of the skin and ensure that it remains firm, smooth and taut.

 

  1. InjectionBiostimulators are injected into the desired areas of the skin or subcutaneous tissue using fine needles or cannulas. This is usually done after the application of an anaesthetic cream so that the treatment causes hardly any pain.

  2. StimulationAfter injection, the biostimulators begin to stimulate the fibroblasts to produce new collagen fibres. Depending on the material used, the biostimulator remains in the tissue for a certain period of time while it is gradually broken down.

  3. Long-term effectThe new collagen fibres that are formed through biostimulation lead to firmer, tighter and smoother skin. The volume build-up occurs naturally and lasts for months to years, depending on the substance and the individual skin conditions.

  4. Step-by-step resultThe effect of the biostimulants starts gradually. An initial improvement is usually seen after a few weeks, with continuous improvement over several months as collagen production gradually increases.

Who are biostimulators suitable for?

Biostimulators are suitable for people who want to combat or prevent signs of skin ageing without resorting to invasive procedures or highly visible volume enhancement procedures. They are particularly suitable for:

 

  • Fine to moderate wrinklesBiostimulants work particularly well for patients who want to compensate for the loss of volume and fine lines caused by the natural ageing process.
  • Loss of volume in the faceAge-related volume loss, especially in the cheeks and jawline, can be effectively treated with biostimulators.
  • Sagging skinWhen the skin loses firmness and elasticity, biostimulants can help to tighten and firm the skin structure.
  • A natural and long-term improvement in skin qualitySince biostimulants rely on the body's own processes, the results are very natural and unfold over a longer period of time.
  • Patients who do not wish to use classic fillersIf you want a subtle improvement without excessive volume, biostimulants are a gentle and natural alternative.
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What results can be expected?

The results of biostimulants are not immediately visible as, unlike fillers, they do not immediately create volume. Instead, collagen begins to build up in the weeks following treatment, leading to natural skin rejuvenation. A significant improvement becomes visible within 6 to 12 weeks, with the skin's appearance continuously improving.

 

The effect usually lasts between one and two years, depending on the biostimulator used and the individual skin conditions. As collagen production is stimulated, the skin remains firmer and more elastic even after the treatment.

Conclusion

Biostimulators offer an effective anti-ageing treatment that relies on natural regeneration processes. By stimulating collagen production, they help to correct volume loss, wrinkles and sagging skin. This treatment method is ideal for people looking for a gentle but long-term improvement in skin quality and offers a natural alternative to classic filler treatments.

 

For detailed informaFor further information and individual advice on biostimulators, please contact our aesthetic medicine practice for a personal consultation.

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